Disseminated herpes simplex virus 2 as a complication of pregnancy

Lauren Bougioukas; Rachel B C Psoinos; David C Jones; Erin A Morris; Andrew J Hale

doi:10.1016/j.idcr.2021.e01107

Disseminated herpes simplex virus 2 as a complication of pregnancy

IDCases. 2021 Mar 31:24:e01107. doi: 10.1016/j.idcr.2021.e01107. eCollection 2021.

Authors

Lauren Bougioukas¹, Rachel B C Psoinos^{1

2}, David C Jones^{1

2

3}, Erin A Morris^{1

2}, Andrew J Hale^{1

2}

Affiliations

¹ Larner College of Medicine, University of Vermont, Burlington, VT, United States.
² University of Vermont Medical Center, United States.
³ Fetal Diagnostic Center, United States.

Abstract

Disseminated herpes simplex virus 2 (HSV-2) infection, is a rare but devastating infection in pregnancy women. We present the case of a 30-year-old gravida 3, para 2-0-0-2, at 26 weeks 2 days gestation who presented with eleven days of vague and indolent symptoms before a diagnosis of disseminated HSV-2 infection with associated hepatitis was made. While the patient clinically improved with empiric acyclovir treatment, possibility of significant harm to the fetus remained, and the patient request elective termination. The authors review the epidemiology, diagnosis, treatment, and prognosis of disseminated HSV-2 infection in pregnancy.

Keywords: Disseminated herpes simplex virus 2; Infectious complications of pregnancy; Pregnancy.

Publication types

Case Reports