A Comprehensive Review on Selenium and Its Effects on Human Health and Distribution in Middle Eastern Countries

Biol Trace Elem Res. 2022 Mar;200(3):971-987. doi: 10.1007/s12011-021-02716-z. Epub 2021 Apr 21.

Abstract

Selenium (Se) is an important microelement with numerous positive effects on human health and diseases. It is important to specify that the status and consumption of Se are for a specific community as the levels of Se are extremely unpredictable between different populations and regions. Our existing paper was based on the impacts of Se on human health and disease along with data on the Se levels in Middle Eastern countries. Overall, the findings of this comprehensive review show that the consumption and levels of Se are inadequate in Middle Eastern nations. Such findings, together with the growing awareness of the importance of Se to general health, require further work primarily on creating an acceptable range of blood Se concentration or other measures to determine optimal Se consumption and, consequently, to guarantee adequate Se supplementation in populations at high risk of low Se intake.

Keywords: GPx; Human health; Middle East; Selenium; Selenoproteins.

Publication types

  • Review

MeSH terms

  • Humans
  • Nutritional Status
  • Selenium*
  • Selenoproteins

Substances

  • Selenoproteins
  • Selenium