The screening test for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) disease 2019 (COVID-19) has not been performed in healthcare workers (HCWs) yet, although HCWs are at a high risk of infection. COVID-19 is detected in 5%-15% of HCWs according to published studies. Nevertheless, it may be higher than the rates indicated in published studies. Based on this fact, the current recommendation of studies in the literature is to screen COVID-19 in HCWs. In this review, studies on SARS-CoV-2 screening in HCWs will be reconsidered, and the frequency and target group in whom screening should be performed will be emphasized.