We documented 4 cases of severe acute respiratory syndrome coronavirus 2 reinfection by non-variant of concern strains among healthcare workers in Campinas, Brazil. We isolated infectious particles from nasopharyngeal secretions during both infection episodes. Improved and continued protection measures are necessary to mitigate the risk for reinfection among healthcare workers.
Keywords: 2019 novel coronavirus disease; Brazil; COVID-19; D614G mutation; MinIon Sequencing; SARS-CoV-2; coronavirus; coronavirus disease; healthcare workers; reinfection; respiratory infections; severe acute respiratory syndrome coronavirus 2; variants; viral shedding; virus isolation; viruses; zoonoses.