Marantic Endocarditis Associated with COVID-19: A Rare Case Report of a Potentially Deadly Disease

Kok Hoe Chan; Ormena Joseph; Eyad Ahmed; Apoorva Kommidi; Addi Suleiman; Maria E Szabela; Jihad Slim

doi:10.12890/2021_002409

Marantic Endocarditis Associated with COVID-19: A Rare Case Report of a Potentially Deadly Disease

Eur J Case Rep Intern Med. 2021 Mar 19;8(3):002409. doi: 10.12890/2021_002409. eCollection 2021.

Authors

Kok Hoe Chan¹, Ormena Joseph¹, Eyad Ahmed¹, Apoorva Kommidi¹, Addi Suleiman^{1

2}, Maria E Szabela^{1

3}, Jihad Slim^{1

3}

Affiliations

¹ Department of Medical Education, Saint Michael's Medical Centre, New York Medical College, Newark, New Jersey, USA.
² Department of Cardiology, Saint Michael's Medical Centre, New York Medical College, Newark, New Jersey, USA.
³ Department of Infectious Disease, Saint Michael's Medical Centre, New York Medical College, Newark, New Jersey, USA.

Abstract

Coronavirus disease 2019 (COVID-19) has overwhelmed healthcare globally with millions of cases and over 2 million deaths worldwide. The hypercoagulable state associated with COVID-19 is a well-recognized complication that carries a poor prognosis. Marantic endocarditis, or non-bacterial thrombotic endocarditis (NBTE), is caused by a sterile vegetation on the cardiac valves resulting from the deposition of fibrin and platelet aggregates. It is highly associated with the hypercoagulable and acquired inflammatory states. Herein, we report a unique and rare case of COVID-19 presenting with NBTE.

Learning points: COVID-19 has caused a major global pandemic, with high morbidity and mortality.One of the complications of COVID-19 infection is a hypercoagulable state.To the best of our knowledge, we present only the second case of marantic endocarditis in a patient with COVID-19, in the hope of raising awareness among physicians of this potential rare association.

Keywords: COVID-19; COVID-19 associated coagulopathy; Marantic endocarditis; hypercoagulable state; non-bacterial thrombotic endocarditis.