Lack of evidence for a role of PIWIL1 variants in human male infertility

Cell. 2021 Apr 15;184(8):1941-1942. doi: 10.1016/j.cell.2021.03.001.
No abstract available

Keywords: D-box; HIWI; MIWI; PIWIL1; azoospermia; clinical validity assessment; exome sequencing; male infertility; oligozoospermia; piRNA; single molecule molecular inversion probes.

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Argonaute Proteins / genetics
  • Argonaute Proteins / metabolism
  • Azoospermia*
  • Humans
  • Infertility, Male* / genetics
  • Male

Substances

  • Argonaute Proteins
  • PIWIL1 protein, human