Angiomatoid fibrous histiocytoma (AFH) unusual clinical presentation and unique radiological findings

BJR Case Rep. 2020 Dec 2;7(2):20190069. doi: 10.1259/bjrcr.20190069. eCollection 2021 Apr 1.

Abstract

Angiomatoid fibrous histiocytoma (AFH) are rare soft tissue mesenchymal neoplasms that commonly affect children and young adults. They are classified as "intermediate tumours of uncertain differentiation". We present a case of an 8-year-old child with a left thigh AFH and antecedent history of minor trauma showing perilesional oedema and enhancement at MRI, leading to an initial working diagnosis of infected haematoma that contributed to the challenge in reaching the final diagnosis. Although most of the imaging features of AFH previously described in the literature are demonstrated in this case, the presence of arterial vascular channels within the tumour and feeding branch from the left profunda femoris artery is unusual and to our knowledge the first to be published in the literature.

Publication types

  • Case Reports