mRNA Transport and Local Translation in Glia

Trends Cell Biol. 2021 Jun;31(6):419-423. doi: 10.1016/j.tcb.2021.03.006. Epub 2021 Apr 8.

Abstract

Though mRNA transport and local translation are extensively studied in neurons, emerging evidence supports that these cellular processes are also abundant in non-neuronal glial cells. Here, we explore mechanisms of mRNA transport and local translation in oligodendrocytes, astrocytes, microglia, radial glia, and their functions in development, structure, and intercellular interactions.

Publication types

  • Research Support, N.I.H., Intramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Astrocytes*
  • Neuroglia*
  • Neurons
  • Oligodendroglia
  • RNA, Messenger

Substances

  • RNA, Messenger