A comprehensive approach to ending an outbreak of rare blaOXA-72 gene-positive carbapenem-resistant Acinetobacter baumannii at a Community Hospital, Kansas City, MO, 2018

David S McKinsey; Carolyn Gasser; Joel P McKinsey; Geri Ditto; Alyssa Agard; Brianna Zellmer; Carrie Poteete; Paula Snippes Vagnone; Jennifer L Dale; John Bos; Rachael Hahn; George Turabelidze; Madison Poiry; Patrick Franklin; Nicholas Vlachos; Gillian A McAllister; Alison Laufer Halpin; Janet Glowicz; D Cal Ham; Lauren Epstein

doi:10.1016/j.ajic.2021.03.022

A comprehensive approach to ending an outbreak of rare bla_OXA-72 gene-positive carbapenem-resistant Acinetobacter baumannii at a Community Hospital, Kansas City, MO, 2018

Am J Infect Control. 2021 Sep;49(9):1183-1185. doi: 10.1016/j.ajic.2021.03.022. Epub 2021 Apr 9.

Authors

David S McKinsey¹, Carolyn Gasser², Joel P McKinsey², Geri Ditto², Alyssa Agard², Brianna Zellmer², Carrie Poteete², Paula Snippes Vagnone³, Jennifer L Dale³, John Bos⁴, Rachael Hahn⁴, George Turabelidze⁴, Madison Poiry⁴, Patrick Franklin⁴, Nicholas Vlachos⁵, Gillian A McAllister⁵, Alison Laufer Halpin⁶, Janet Glowicz⁵, D Cal Ham⁵, Lauren Epstein⁵

Affiliations

¹ Research Medical Center, Kansas City, MO. Electronic address: david.mckinsey@hcamidwest.com.
² Research Medical Center, Kansas City, MO.
³ Minnesota Department of Health Public Health Laboratory, Infectious Disease Section, St. Paul, MN.
⁴ Missouri Department of Health and Senior Services, Jefferson City MO.
⁵ Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, GA.
⁶ Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, GA; Commissioned Corps, U.S. Public Health Service, Rockville MD.

PMID: 33839188
DOI: 10.1016/j.ajic.2021.03.022

Abstract

We identified a cluster of extensively drug-resistant, carbapenemase gene-positive, carbapenem-resistant Acinetobacter baumannii (CP-CRAB) at a teaching hospital in Kansas City. Extensively drug-resistant CRAB was identified from eight patients and 3% of environmental cultures. We used patient cohorting and targeted environmental disinfection to stop transmission. After implementation of these measures, no additional cases were identified.

Keywords: Cohorting; Environmental contamination; Outbreak control.

MeSH terms

Acinetobacter Infections* / drug therapy
Acinetobacter Infections* / epidemiology
Acinetobacter Infections* / prevention & control
Acinetobacter baumannii* / genetics
Anti-Bacterial Agents / pharmacology
Anti-Bacterial Agents / therapeutic use
Bacterial Proteins / genetics
Carbapenems / pharmacology
Cross Infection* / drug therapy
Cross Infection* / epidemiology
Cross Infection* / prevention & control
Disease Outbreaks
Drug Resistance, Multiple, Bacterial
Hospitals, Community
Humans
Kansas / epidemiology
Microbial Sensitivity Tests
beta-Lactamases / genetics

Substances

Anti-Bacterial Agents
Bacterial Proteins
Carbapenems
beta-Lactamases