Painless rash in a transplant patient

Transpl Infect Dis. 2021 Aug;23(4):e13613. doi: 10.1111/tid.13613. Epub 2021 Apr 27.

Abstract

Dermatophytes are common keratinophilic fungi responsible for superficial skin infections. Deep dermatophytosis is a rare form of invasive skin infection described in immunocompromised patients. We report the case of a 65-year-old man with a history of an orthotopic liver transplant for hepatocarcinoma 6 months earlier, who presented with small painless erythematous papules in lower limbs, some of which were umbilicated. Skin biopsy showed an intense non-necrotizing granulomatous reaction in the dermis around fungal structures. Trichophyton rubrum was identified as the causal agent through culture and internal transcribed spacer sequencing.

Keywords: Trichophyton rubrum; deep dermatophytosis; organ transplant.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Arthrodermataceae
  • Exanthema*
  • Humans
  • Male
  • Skin
  • Tinea* / diagnosis
  • Tinea* / drug therapy
  • Trichophyton / genetics

Supplementary concepts

  • Trichophyton rubrum