Urgent lung transplantation for thymic neoplasm-associated severe constrictive bronchiolitis with bronchiectasis and radiotherapy-induced organizing pneumonia: A case report

Thorac Cancer. 2021 Jun;12(11):1757-1760. doi: 10.1111/1759-7714.13936. Epub 2021 Apr 8.

Abstract

Here, we present the case of a 28-year-old woman who developed severe and progressive thymoma-associated constrictive bronchiolitis with bronchiectasis, despite undergoing thymectomy. The disease was further complicated by radiation-induced organizing pneumonia (RIOP), which developed after adjuvant radiotherapy (RT) for Masaoka stage II thymoma. The patient was successfully treated with an urgent lung transplantation (LTx) for irreversible respiratory failure.

Keywords: end-stage lung disease; lung transplantation; radiation induced organizing pneumonia; thymic neoplasm-associated bronchiolitis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Bronchiectasis / therapy*
  • Bronchiolitis Obliterans / therapy*
  • Female
  • Humans
  • Lung Transplantation / methods*
  • Radiation Pneumonitis / therapy*
  • Thymus Neoplasms / therapy*