Complications associated with continuous renal replacement therapy

Karthik Kovvuru; Juan C Q Velez

doi:10.1111/sdi.12970

Complications associated with continuous renal replacement therapy

Semin Dial. 2021 Nov;34(6):489-494. doi: 10.1111/sdi.12970. Epub 2021 Apr 7.

Authors

Karthik Kovvuru^{1

2}, Juan C Q Velez^{1

3}

Affiliations

¹ Ochsner Medical Center, Department of Nephrology, New Orleans, LA, USA.
² Ochsner Medical Center, Department of Critical Care Medicine, New Orleans, LA, USA.
³ Ochsner Clinical School, The University of Queensland (Brisbane), New Orleans, LA, USA.

PMID: 33827146
DOI: 10.1111/sdi.12970

Abstract

With the evolution of standardized replacement fluids, newer machines, and high flux membranes, continuous renal replacement therapy (CRRT) has made remarkable progress in the field of extracorporeal therapies. CRRT is the preferred dialytic modality for patients in intensive care unit setting (ICU). Standardized protocols are implemented by many institutions to avoid errors and ensure patient safety. However, complications related to CRRT are not uncommon. Understanding CRRT operations is essential to analyze the complications and further assist in developing measures to mitigate the risk. Overview of CRRT complications and potential preventive strategies are discussed in the current review.

Keywords: CRRT complications; citrate toxicity; continuous renal replacement therapy; filter clogging; filter clotting.

Publication types

Review

MeSH terms

Acute Kidney Injury* / therapy
Anticoagulants
Continuous Renal Replacement Therapy* / adverse effects
Humans
Intensive Care Units
Renal Dialysis
Renal Replacement Therapy / adverse effects

Substances

Anticoagulants