O group is a protective factor for COVID19 in Basque population

PLoS One. 2021 Apr 7;16(4):e0249494. doi: 10.1371/journal.pone.0249494. eCollection 2021.

Abstract

ABO blood groups have recently been related to COVID19 infection. In the present work, we performed this analysis using data from 412 COVID19 patients and 17796 blood donors, all of them from Gipuzkoa, a region in Northern Spain. The results obtained confirmed this relation, in addition to showing a clear importance of group O as a protective factor in COVID19 disease, with an OR = 0.59 (CI95% 0.481-0.7177, p<0.0001) while A, B and AB are risk factors. ABO blood groups are slightly differently distributed in the populations and therefore these results should be replicated in the specific areas with a proper control population.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • ABO Blood-Group System*
  • Aged
  • Blood Donors / classification*
  • COVID-19 / blood
  • COVID-19 / epidemiology*
  • COVID-19 / prevention & control
  • Humans
  • Middle Aged
  • Protective Factors
  • Spain / ethnology

Substances

  • ABO Blood-Group System

Grants and funding

This project has been supported by Instituto de Salud Carlos III (COV20/00314) that includes European Support (FEDER). There was no additional external funding received for this study. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.