How Traumatic is Intravitreal Ozurdex Injection?

Ocul Immunol Inflamm. 2023 Oct;31(8):1569-1571. doi: 10.1080/09273948.2021.1896009. Epub 2021 Apr 7.

Abstract

Background: This study intended to illustrate a rare case of pyogenic granuloma (PG) in retinal vein occlusion (RVO) patient after dexamethasone (DEX) implant therapy.

Case description: A 58-year-old female who underwent DEX implant therapy a month ago due to RVO presented with a mass in her right eye. Anterior segment analysis revealed a slowly enlarging, round, fleshy vascular mass indicating PG located at the injection site. Although surgical excision was planned, because of the Covid-19 pandemic, a patient could not come for surgery. Ocular examination revealed a spontaneous PG disappearance three months later. A small mass could, however, be detected using an anterior segment optical coherence tomography.

Conclusion: While superficial PG regression can only be observed by slit-lamp biomicroscopy, extensive root ingrowth can be clearly differentiated by anterior segment optical coherence tomography. Besides, depending on the nature, size, location, and associated symptoms, some PG may be left to regress but with close monitoring.

Keywords: Anterior segment OCT; Ozurdex; anterior segment photography; pyogenic granuloma; retinal vein occlusion.

Publication types

  • Case Reports

MeSH terms

  • COVID-19*
  • Dexamethasone / therapeutic use
  • Drug Implants / adverse effects
  • Female
  • Glucocorticoids / therapeutic use
  • Humans
  • Intravitreal Injections
  • Middle Aged
  • Pandemics
  • Retinal Vein Occlusion* / diagnosis
  • Retinal Vein Occlusion* / drug therapy
  • Tomography, Optical Coherence
  • Visual Acuity

Substances

  • Glucocorticoids
  • Drug Implants
  • Dexamethasone