[Sinus node dysfunction associated with cardiac sarcoidosis: A case report]

L-D Azoulay; D Perrot; A Sharifzadehgan; E Mousseaux; E Marijon; T Lavergne

doi:10.1016/j.revmed.2021.02.013

[Sinus node dysfunction associated with cardiac sarcoidosis: A case report]

Rev Med Interne. 2021 Sep;42(9):654-659. doi: 10.1016/j.revmed.2021.02.013. Epub 2021 Apr 3.

[Article in French]

Authors

L-D Azoulay¹, D Perrot², A Sharifzadehgan³, E Mousseaux⁴, E Marijon⁵, T Lavergne⁶

Affiliations

¹ Service de cardiologie, unité de rythmologie, hôpital européen Georges-Pompidou, Université de Paris, Assistance publique-Hôpitaux de Paris, 75015 Paris, France. Electronic address: azoulaylevidan@gmail.com.
² Service de cardiologie, unité de rythmologie, hôpital européen Georges-Pompidou, Université de Paris, Assistance publique-Hôpitaux de Paris, 75015 Paris, France. Electronic address: david.perrot@aphp.fr.
³ Service de cardiologie, unité de rythmologie, hôpital européen Georges-Pompidou, Université de Paris, Assistance publique-Hôpitaux de Paris, 75015 Paris, France. Electronic address: ardalan.sharifzadehgan@aphp.fr.
⁴ Service de radiologie, hôpital européen Georges-Pompidou, Université de Paris, Assistance publique-Hôpitaux de Paris, 75015 Paris, France. Electronic address: elie.mousseaux@aphp.fr.
⁵ Service de cardiologie, unité de rythmologie, hôpital européen Georges-Pompidou, Université de Paris, Assistance publique-Hôpitaux de Paris, 75015 Paris, France. Electronic address: eloi.marijon@aphp.fr.
⁶ Service de cardiologie, unité de rythmologie, hôpital européen Georges-Pompidou, Université de Paris, Assistance publique-Hôpitaux de Paris, 75015 Paris, France. Electronic address: thomas.lavergne@aphp.fr.

PMID: 33824044
DOI: 10.1016/j.revmed.2021.02.013

Abstract

Introduction: Sarcoidosis is a multisystemic granulomatous disease of unknown cause occurring in young adults. Cardiac sarcoidosis patients are at increased risk for atrioventricular blocks and ventricular arrhythmias. Sinus node dysfunction is scarcely reported.

Observation: We report a case of cardiac sarcoidosis revealed by a sinus node dysfunction and focus on cardiac and thoracic imaging to guide diagnosis.

Conclusion: Sinus node dysfunction may be the first manifestation of cardiac sarcoidosis. In unexplained sinus node dysfunction in young patients, advanced cardiac imaging is a key to cardiac sarcoidosis diagnostic. Early recognition of cardiac sarcoidosis enables to start immunosuppressive treatment and discuss implantable cardioverter defibrillator implantation.

Publication types

Case Reports

MeSH terms

Arrhythmias, Cardiac
Cardiomyopathies* / complications
Cardiomyopathies* / diagnosis
Defibrillators, Implantable*
Humans
Sarcoidosis* / complications
Sarcoidosis* / diagnosis
Sick Sinus Syndrome / complications
Sick Sinus Syndrome / diagnosis
Sick Sinus Syndrome / therapy
Young Adult