Early therapeutic lamellar keratoplasty for acanthamoeba keratitis followed by implantable Collamer lens for visual rehabilitation

Middle East Afr J Ophthalmol. 2021 Jan 19;27(4):244-246. doi: 10.4103/meajo.meajo_557_20. eCollection 2020 Oct-Dec.

Abstract

We are reporting the case of a 25-year-old female who developed acanthamoeba keratitis after wearing contact lenses for high myopia. She was diagnosed as acanthamoeba and started the treatment of antiacanthamoeba for 3 consecutive weeks, followed by bare Descemet's therapeutic lamellar keratoplasty (LKP) with the maintenance of antiacanthamoeba treatment to control the infection. In the late postoperative period, visual rehabilitation was obtained by insertion of implantable Collamer lens (ICL) with her final visual outcome was 20/30. For acanthamoeba keratitis, early bare Descemet's therapeutic LKP has a better outcome in comparison to late penetrating keratoplasty in terms of infection eradication and globe preservation. After removal of all sutures, the refractive error can be corrected with photorefractive procedures as well as ICL.

Keywords: Acanthamoeba keratitis; bare Descemet's therapeutic lamellar keratoplasty; implantable Collamer lens; refractive error.

Publication types

  • Case Reports

MeSH terms

  • Acanthamoeba Keratitis / drug therapy
  • Acanthamoeba Keratitis / surgery
  • Acanthamoeba Keratitis / therapy*
  • Adult
  • Anti-Infective Agents, Local / therapeutic use*
  • Antifungal Agents / therapeutic use*
  • Benzamidines / therapeutic use
  • Chlorhexidine / therapeutic use
  • Corneal Transplantation*
  • Drug Therapy, Combination
  • Female
  • Fluconazole / therapeutic use
  • Humans
  • Lenses, Intraocular*
  • Slit Lamp Microscopy
  • Vision Disorders / rehabilitation*
  • Visual Acuity / physiology

Substances

  • Anti-Infective Agents, Local
  • Antifungal Agents
  • Benzamidines
  • dibrompropamidine
  • Fluconazole
  • Chlorhexidine