Progressive Multifocal Leukoencephalopathy Following Treatment With Obinutuzumab in a Patient With Non-Hodgkin Follicular Lymphoma: A Case Report

Clin Lymphoma Myeloma Leuk. 2021 Jul;21(7):e601-e605. doi: 10.1016/j.clml.2021.02.016. Epub 2021 Mar 4.

Authors

Stavrianna Diavati¹, John V Asimakopoulos¹, Dimitrios Galopoulos¹, Iliana Konstantinou¹, Theodore Argyrakos², Panagiotis Toulas³, Theodoros P Vassilakopoulos¹, Kostas Konstantopoulos¹, Maria K Angelopoulou⁴

Affiliations

¹ Department of Haematology and Bone Marrow Transplantation, Laikon General Hospital, National and Kapodistrian University of Athens, Athens, Greece.
² Department of Pathology, Evaggelismos Hospital, Athens, Greece.
³ Department of Radiology, Biiatrics Group Diagnostic Centers, Athens, Greece.
⁴ Department of Haematology and Bone Marrow Transplantation, Laikon General Hospital, National and Kapodistrian University of Athens, Athens, Greece. Electronic address: mkangelop@gmail.com.

PMID: 33814337
DOI: 10.1016/j.clml.2021.02.016

No abstract available

Keywords: Anti-CD20(+) era; First report; JC polyoma virus; Novel treatments; Relapsing.

Publication types

Case Reports

MeSH terms

Aged
Antibodies, Monoclonal, Humanized / adverse effects*
Antineoplastic Agents, Immunological / adverse effects*
Brain / diagnostic imaging
Brain / pathology
DNA, Viral / isolation & purification
Fatal Outcome
Female
Humans
Immunocompromised Host
JC Virus / genetics
JC Virus / immunology
JC Virus / isolation & purification
Leukoencephalopathy, Progressive Multifocal / blood
Leukoencephalopathy, Progressive Multifocal / chemically induced
Leukoencephalopathy, Progressive Multifocal / diagnosis*
Leukoencephalopathy, Progressive Multifocal / immunology
Lymphoma, Follicular / drug therapy*
Lymphoma, Follicular / immunology
Magnetic Resonance Imaging
Neoplasm Recurrence, Local / drug therapy*
Neoplasm Recurrence, Local / immunology

Substances

Antibodies, Monoclonal, Humanized
Antineoplastic Agents, Immunological
DNA, Viral
obinutuzumab