A novel NECTIN4-NTRK1 fusion identified in a lung squamous cell carcinoma patient with MSI-H

J Cancer Res Clin Oncol. 2021 Aug;147(8):2483-2486. doi: 10.1007/s00432-021-03622-6. Epub 2021 Apr 3.

Authors

Peng Li¹, Feng Hou², Sai Wang¹, Ningning Luo³, Yingxue Qi³, Yongjie Wang⁴

Affiliations

¹ Department of Thoracic Surgery, Qingdao University, Qingdao, China.
² Department of Pathology, The Affiliated Hospital of Qingdao University, Qingdao, China.
³ The Medical Department, Jiangsu Simcere Diagnostics Co., Ltd, Nanjing Simcere Medical Laboratory Science Co., Ltd, The State Key Lab of Translational Medicine and Innovative Drug Development, Jiangsu Simcere Diagnostics Co., Ltd, Nanjing, China.
⁴ Department of Thoracic Surgery, The Affiliated Hospital of Qingdao University, Qingdao, China. wyjtgzy@163.com.

PMID: 33811536
DOI: 10.1007/s00432-021-03622-6

No abstract available

Publication types

Letter

MeSH terms

Carcinoma, Squamous Cell / diagnosis*
Carcinoma, Squamous Cell / genetics*
Carcinoma, Squamous Cell / therapy
Cell Adhesion Molecules / genetics*
DNA Mutational Analysis
Genetic Association Studies
Genetic Predisposition to Disease
High-Throughput Nucleotide Sequencing
Humans
Immunohistochemistry
In Situ Hybridization, Fluorescence
Lung Neoplasms / diagnosis*
Lung Neoplasms / genetics*
Male
Microsatellite Instability*
Middle Aged
Oncogene Proteins, Fusion*
Positron Emission Tomography Computed Tomography
Receptor, trkA / genetics*

Substances

Cell Adhesion Molecules
NTRK1 protein, human
Oncogene Proteins, Fusion
NECTIN4 protein, human
Receptor, trkA