Repeat Coronary Artery Bypass Grafting: A Meta-Analysis of Off-Pump versus On-Pump Techniques in a Large Cohort of Patients

Heart Lung Circ. 2021 Sep;30(9):1281-1291. doi: 10.1016/j.hlc.2021.02.015. Epub 2021 Mar 31.

Abstract

Background: Redo coronary artery bypass grafting (CABG) can be performed with either the off-pump (OPCAB) or the on-pump (ONCAB) technique.

Method: Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA), this meta-analysis compared the safety and efficacy of OPCAB versus ONCAB redo CABG.

Results: Twenty-three (23) eligible studies were included (OPCAB, n=2,085; ONCAB, n=3,245). Off-pump CABG significantly reduced the risk of perioperative death (defined as in-hospital or 30-day death rate), myocardial infarction, atrial fibrillation, and acute kidney injury. The two treatment approaches were comparable regarding 30-day stroke and late all-cause mortality.

Conclusions: Off-pump redo CABG resulted in lower perioperative death and periprocedural complication rates. No difference was observed in perioperative stroke rates and long-term survival between the two techniques.

Keywords: Coronary artery bypass graft; Off-pump; On-pump; Re-operative cardiac surgery; Redo CABG.

Publication types

  • Meta-Analysis
  • Review

MeSH terms

  • Atrial Fibrillation* / surgery
  • Cohort Studies
  • Coronary Artery Bypass
  • Coronary Artery Bypass, Off-Pump*
  • Humans
  • Stroke* / epidemiology
  • Stroke* / etiology
  • Treatment Outcome