Bone Density Micro-CT Assessment during Embedding of the Innovative Multi-Spiked Connecting Scaffold in Periarticular Bone to Elaborate a Validated Numerical Model for Designing Biomimetic Fixation of Resurfacing Endoprostheses

Ryszard Uklejewski; Mariusz Winiecki; Adam Patalas; Piotr Rogala

doi:10.3390/ma14061384

Bone Density Micro-CT Assessment during Embedding of the Innovative Multi-Spiked Connecting Scaffold in Periarticular Bone to Elaborate a Validated Numerical Model for Designing Biomimetic Fixation of Resurfacing Endoprostheses

Materials (Basel). 2021 Mar 12;14(6):1384. doi: 10.3390/ma14061384.

Authors

Ryszard Uklejewski^{1

2}, Mariusz Winiecki^{1

2}, Adam Patalas², Piotr Rogala^{2

3}

Affiliations

¹ Chair of Construction Materials and Biomaterials, Institute of Materials Engineering, Kazimierz Wielki University, 85-064 Bydgoszcz, Poland.
² Laboratory of Bone Implants Research and Design, Department of Technology Design, Institute of Mechanical Technology, Poznan University of Technology, 60-965 Poznan, Poland.
³ Institute of Health Sciences, Hipolit Cegielski State College of Higher Education, 62-200 Gniezno, Poland.

Abstract

Our team has been working for some time on designing a new kind of biomimetic fixation of resurfacing endoprostheses, in which the innovative multi-spiked connecting scaffold (MSC-Scaffold) that mimics the natural interface between articular cartilage and periarticular trabecular bone in human joints is the crucial element. This work aimed to develop a numerical model enabling the design of the considered joint replacement implant that would reflect the mechanics of interacting biomaterials. Thus, quantitative micro-CT analysis of density distribution in bone material during the embedding of MSC-Scaffold in periarticular bone was applied. The performed numerical studies and corresponding mechanical tests revealed, under the embedded MSC-Scaffold, the bone material densification affecting its mechanical properties. On the basis of these findings, the built numerical model was modified by applying a simulated insert of densified bone material. This modification led to a strong correlation between the re-simulation and experimental results (FVU = 0.02). The biomimetism of the MSC-Scaffold prototype that provided physiological load transfer from implant to bone was confirmed based on the Huber-von Mises-Hencky (HMH) stress maps obtained with the validated finite element (FE) model of the problem. The micro-CT bone density assessment performed during the embedding of the MSC-Scaffold prototype in periarticular bone provides insight into the mechanical behaviour of the investigated implant-bone system and validates the numerical model that can be used for the design of material and geometric features of a new kind of resurfacing endoprostheses fixation.

Keywords: biomimetic fixation for resurfacing endoprostheses; micro-CT assessment; multi-spiked connecting scaffold (MSC-Scaffold); periarticular bone density; validated numerical model.