An Inside Look into Biological Miniatures: Molecular Mechanisms of Viroids

Int J Mol Sci. 2021 Mar 10;22(6):2795. doi: 10.3390/ijms22062795.

Abstract

Viroids are tiny single-stranded circular RNA pathogens that infect plants. Viroids do not encode any proteins, yet cause an assortment of symptoms. The following review describes viroid classification, molecular biology and spread. The review also discusses viroid pathogenesis, host interactions and detection. The review concludes with a description of future prospects in viroid research.

Keywords: classification; evolution; gene silencing; identification; pathogenicity; replication; rolling circle; trafficking; viroid-host interactions; viroids.

Publication types

  • Review

MeSH terms

  • Disease Resistance / genetics
  • Host-Pathogen Interactions
  • Models, Genetic
  • Plant Diseases / genetics
  • Plant Diseases / virology
  • Plants / genetics
  • Plants / virology
  • RNA, Circular / genetics*
  • RNA, Viral / genetics*
  • Viroids / classification
  • Viroids / genetics*
  • Viroids / pathogenicity
  • Virulence / genetics
  • Virus Replication / genetics*

Substances

  • RNA, Circular
  • RNA, Viral