The Physiological TMPRSS2 Inhibitor HAI-2 Alleviates SARS-CoV-2 Infection

J Virol. 2021 May 24;95(12):e00434-21. doi: 10.1128/JVI.00434-21. Print 2021 May 24.
No abstract available

Keywords: HAI-2; SARS-CoV-2; TMPRSS2.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • COVID-19 / genetics
  • COVID-19 / metabolism*
  • Chlorocebus aethiops
  • HEK293 Cells
  • Humans
  • Membrane Glycoproteins / genetics
  • Membrane Glycoproteins / metabolism*
  • SARS-CoV-2 / genetics
  • SARS-CoV-2 / metabolism*
  • Serine Endopeptidases / genetics
  • Serine Endopeptidases / metabolism*
  • Vero Cells

Substances

  • Membrane Glycoproteins
  • SPINT2 protein, human
  • Serine Endopeptidases
  • TMPRSS2 protein, human