Have you ever heard of Human Papillomavirus (HPV) vaccine? The awareness of HPV vaccine for college students in China based on meta-analysis

Gang Yin; Yulin Zhang; Chaoyi Chen; Huayu Ren; Botang Guo; Meng Zhang

doi:10.1080/21645515.2021.1899731

Have you ever heard of Human Papillomavirus (HPV) vaccine? The awareness of HPV vaccine for college students in China based on meta-analysis

Hum Vaccin Immunother. 2021 Aug 3;17(8):2736-2747. doi: 10.1080/21645515.2021.1899731. Epub 2021 Mar 31.

Authors

Gang Yin¹, Yulin Zhang², Chaoyi Chen¹, Huayu Ren³, Botang Guo⁴, Meng Zhang³

Affiliations

¹ Department of Health Administration, School of Medicine and Health Management, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
² Department of Business Administration, School of Economics and Management, Wuchang Institute of Technology, Wuhan, China.
³ Department of Ideological and Political Education, School of Marxism, Harbin Medical University, Harbin, China.
⁴ Department of Medical Psychology, School of Health Management, Harbin Medical University, Harbin, China.

Abstract

Objective: To evaluate the awareness of College Students (CSs) of HPV vaccine in China and provide evidence-based recommendations for HPV vaccine's publicity and promotion.Methods: Web of Science, PubMed, Science of Direct, EBSCO, China National Knowledge Infrastructure and Wanfang Data were searched. A random effects meta-analysis was conducted to determine pooled estimates of Awareness Rate (AR) for HPV vaccine.Results: Of the 36 studies included, the estimated AR of HPV vaccine was 40.27% (95% CI: 30.86%, 50.06%) among Chinese CSs. The AR of HPV vaccine was stratified by factors as gender, major, area, city, survey time, and sampling method of the study. The pooled AR of HPV vaccine among CSs was as follows: 44.17% (95% CI: 31.65%, 57.09%) and 31.93% (95% CI: 13.25%, 54.30%) for females and males; 44.47% (95% CI: 29.90%, 59.55%) and 12.02% (95% CI: 7.69%, 17.15%) for medical-related and nonmedical majors; 44.47% (95% CI: 28.71-60.82%) and 41.16% (95% CI: 26.48-56.64%) for Eastern and Midwestern region; 48.86% (95% CI: 30.63-67.25%) and 33.19% (95% CI: 22.27-45.12%) for first-tier and second- and third-tier city; 29.67 (95% CI: 11.44-52.16%) and 38.81 (95% CI: 27.14-51.21%) for AR before and after HPV vaccine entered in China; 51.51% (95% CI: 32.21%, 70.53%) and 26.21% (95% CI: 17.41%, 36.10%) for nonrandom and random sampling.Conclusion: This review indicates that awareness of HPV vaccine among CSs remains relatively low in China compared with European countries. Our findings may provide useful information to better understand the HPV vaccine awareness status among Chinese CSs.

Keywords: HPV vaccine; Human papillomavirus vaccine; awareness rate; meta-analysis.

Publication types

Meta-Analysis
Research Support, Non-U.S. Gov't
Review

MeSH terms

Alphapapillomavirus*
China / epidemiology
Female
Health Knowledge, Attitudes, Practice
Humans
Male
Papillomavirus Infections* / epidemiology
Papillomavirus Infections* / prevention & control
Papillomavirus Vaccines*
Patient Acceptance of Health Care
Students
Surveys and Questionnaires
Uterine Cervical Neoplasms*
Vaccination

Substances

Papillomavirus Vaccines

Grants and funding

This study was supported by Overseas Returnees Science Foundation of Heilongjiang [grant number: LC2011C41], and Sichuan Philosophy & Social Science Project [grant number: YF13-Y11]. The funding body has no role in the manuscript writing and publication.