Is there a role for physical activity interventions in the treatment pathway of bladder cancer? A scoping review of the literature

Agustina Bessa; Cecilia Bosco; Sneha Mehrotra; Megan Rowland; Hanyu Zhang; Beth Russell; Louis Fox; Katharina Beyer; Elke Rammant; Suzanne Amery; Kathryn Chatterton; Nicola Peat; Christel Haggstrom; Mieke Van Hemelrijck

doi:10.1136/bmjsem-2020-000951

Is there a role for physical activity interventions in the treatment pathway of bladder cancer? A scoping review of the literature

BMJ Open Sport Exerc Med. 2021 Mar 10;7(1):e000951. doi: 10.1136/bmjsem-2020-000951. eCollection 2021.

Authors

Affiliations

¹ Translational Oncology Urology Research, King's College London, London, UK.
² Faculty of Life Sciences and Medicine, King's College London, London, UK.
³ King's College London - Strand Campus, London, London, UK.
⁴ Ghent University, Ghent, Belgium.
⁵ Guy's and St Thomas' NHS Foundation Trust, London, UK.
⁶ Uppsala Universitet, Uppsala, Sweden.

Abstract

Introduction: Physical activity (PA) interventions have been introduced in patients with cancer as they may contribute to better treatment outcomes and quality of life (QoL). However, little is known about the impact of PA on patients with bladder cancer (BC). This scoping review aimed to explore efficacy and feasibility of existing PA interventions in the BC care pathway.

Methods and analysis: Preferred Reporting Items for Systematic Reviews and Meta-Analyses Scoping Review guidelines and the Levac methodology framework were used; electronic databases were searched. Two independent reviewers screened all titles, abstracts and full-text publications for inclusion. The feasibility of integrating a PA intervention in the BC treatment pathway was discussed in a consultation phase with healthcare professionals and patient and public representatives.

Results: A total of 675 records were identified through database searching of which 14 studies were included in our scoping review. An additional 17 clinical trials were identified of which 12 were included for which no results have been published yet. The included studies looked at the feasibility of a PA intervention programme, the associations between PA, obesity and BC, but also the determinants of PA engagement for BC patients and the assessment of QoL.

Conclusion: This scoping review highlights that despite the general recognition on the role of PA in the BC treatment pathway, there is a gap regarding the understanding of the impact of PA interventions in BC care pathways as well as the limited understanding of factors underlying possible benefits of PA. No clear conclusions could be made regarding structure and processes of PA interventions that may lead to better outcomes. Further PA studies for patients with BC are needed to understand how to incorporate exercise guidelines recommendations.

Keywords: cancer; sport and exercise psychology; urology.