Updates in neonatal coronavirus disease 2019: What can we learn from detailed case reports? (Review)

Mol Med Rep. 2021 May;23(5):351. doi: 10.3892/mmr.2021.11990. Epub 2021 Mar 24.

Abstract

Although the COVID‑19 epidemic has lasted for months, it has not yet been successfully controlled, and little is known about neonatal COVID‑19. Therefore, literature search was conducted for references in PubMed, Science Direct, ProQuest, Web of Science and China National Knowledge Infrastructure for detailed case reports on neonatal COVID‑19 published as of July 15, 2020, to facilitate the clinical treatment, epidemic prevention and control of neonatal COVID‑19. Forty nonoverlapping case reports focusing mainly on the demographic characteristics, transmission modes, clinical features, treatments and prognosis of neonatal COVID‑19, including 3 in Chinese and 37 in English, were available.

Keywords: neonate; coronavirus disease 2019; severe acute respiratory syndrome coronavirus 2; characteristics.

Publication types

  • Review

MeSH terms

  • Antibodies, Viral / analysis
  • Antiviral Agents / therapeutic use
  • Asymptomatic Diseases
  • COVID-19 / pathology*
  • COVID-19 / transmission
  • COVID-19 / virology
  • COVID-19 Drug Treatment
  • Humans
  • Infant, Newborn
  • Milk, Human / virology
  • RNA, Viral / metabolism
  • SARS-CoV-2 / genetics
  • SARS-CoV-2 / immunology
  • SARS-CoV-2 / isolation & purification
  • SARS-CoV-2 / physiology*
  • Thorax / diagnostic imaging

Substances

  • Antibodies, Viral
  • Antiviral Agents
  • RNA, Viral

Grants and funding

The current study was supported by the Scientific and Technological Project of Shiyan City of Hubei Province (grant no. 18Y28).