Post-operative septic arthritis after arthroscopy: modern diagnostic and therapeutic concepts

Knee Surg Sports Traumatol Arthrosc. 2021 Oct;29(10):3149-3158. doi: 10.1007/s00167-021-06525-8. Epub 2021 Mar 23.

Abstract

Purpose: Septic arthritis is a significant complication following arthroscopic surgery, with an estimated overall incidence of less than 1%. Despite the low incidence, an appropriate diagnostic and therapeutic pathway is required to avoid serious long-term consequences, eradicate the infection, and ensure good treatment outcomes. The aim of this current review article is to summarize evidence-based literature regarding diagnostic and therapeutic options of post-operative septic arthritis after arthroscopy.

Methods: Through a literature review, up-to-date treatment algorithms and therapies have been identified. Additionally, a supportive new algorithm is proposed for diagnosis and treatment of suspected septic arthritis following arthroscopic intervention.

Results: A major challenge in diagnostics is the differentiation of the post-operative status between a non-infected hyperinflammatory joint versus septic arthritis, due to clinical symptoms, (e.g., rubor, calor, or tumor) can appear identical. Therefore, joint puncture for microbiological evaluation, especially for fast leukocyte cell-count diagnostics, is advocated. A cell count of more than 20.000 leukocyte/µl with more than 70% of polymorphonuclear cells is the generally accepted threshold for septic arthritis.

Conclusion: The therapy is based on arthroscopic or open surgical debridement for synovectomy and irrigation of the joint, in combination with an adequate antibiotic therapy for 6-12 weeks. Removal of indwelling hardware, such as interference screws for ACL repair or anchors for rotator cuff repair, is recommended in chronic cases.

Level of evidence: IV.

Keywords: Ankle; Antibiotics; Arthroscopy; Complication; Elbow; Hip; Joint infection; Knee; Shoulder; Wrist.

Publication types

  • Review

MeSH terms

  • Arthritis, Infectious* / diagnosis
  • Arthritis, Infectious* / etiology
  • Arthritis, Infectious* / therapy
  • Arthroscopy*
  • Debridement
  • Humans
  • Synovectomy
  • Therapeutic Irrigation
  • Treatment Outcome