Effect of center-based or home-based resistance training on muscle strength and VO2 peak in patients with HFrEF: A systematic review and meta-analysis

Denny Maurits Ruku; Thu Hang Tran Thi; Hsing-Mei Chen

doi:10.1016/j.enfcli.2021.01.011

Effect of center-based or home-based resistance training on muscle strength and VO₂ peak in patients with HFrEF: A systematic review and meta-analysis

Enferm Clin (Engl Ed). 2021 Mar 9:S1130-8621(21)00040-1. doi: 10.1016/j.enfcli.2021.01.011. Online ahead of print.

[Article in English, Spanish]

Authors

Denny Maurits Ruku¹, Thu Hang Tran Thi², Hsing-Mei Chen³

Affiliations

¹ Department of Nursing, College of Medicine, National Cheng Kung University, Taiwan; Faculty of Nursing, Universitas Klabat Airmadidi, Manado 95371, Indonesia.
² Department of Nursing, College of Medicine, National Cheng Kung University, Taiwan; Faculty of Nursing and Medical Technology, The Pham Ngoc Thach University of Medicine, Vietnam.
³ Department of Nursing, College of Medicine, National Cheng Kung University, Taiwan. Electronic address: hsingmei@mail.ncku.edu.tw.

PMID: 33712390
DOI: 10.1016/j.enfcli.2021.01.011

Abstract

Objective: To analyze the components of resistance training (RT) exercises and evaluate the effects of RT on improving muscle strength and oxygen consumption (VO₂) peak based on either center-based rehabilitation or home-based rehabilitation in patients with heart failure with reduced ejection fraction (HFrEF).

Methods: According to the PRISMA guidelines, articles were searched through five databases, including Embase, MEDLINE, CINAHL, PEDro and Cochrane. RevMan 5.3 software was used to perform the meta-analysis.

Results: Nine randomized controlled trial studies met the study criteria, including a total of 299 respondents. In the center-based respondents (n=81 for intervention group vs. n=81 for control group), RT resulted in significant effects on both muscle strength of lower extremity (SDM=1.46, 95% CI=0.41-2.50, n=151) and upper extremity (SDM=0.46, 95% CI=0.05-0.87, n=97) and VO₂ peak (MD=1.45ml/kg/min, 95% CI=0.01-2.89, n=114). In the home-based respondents (n=71 for intervention group vs. n=66 for control group), RT resulted in significant effects on muscle strength of both lower extremity (SDM=0.58, 95% CI: 0.20-0.97, n=113) and upper extremity (SDM=0.84, 95% CI: 0.24-1.44, n=47) and VO₂ peak (MD=5.43ml/kg/min, 95% CI: 0.23-10.62, n=89).

Conclusion: The RT exercise could increase muscle strength and VO₂ peak at either center-based or home-based rehabilitation and should be considered as a part of the care of patients with HFrEF.

Keywords: Center-based rehabilitation; Entrenamiento de resistencia; Fuerza muscular; Heart failure; Home-based rehabilitation; Insuficiencia cardiaca; Muscle strength; Pico de VO2; Rehabilitación domiciliaria; Rehabilitación en centros; Resistance training; VO(2) peak.