Research on multi-path dense networks for MRI spinal segmentation

PLoS One. 2021 Mar 12;16(3):e0248303. doi: 10.1371/journal.pone.0248303. eCollection 2021.

Abstract

Accurate and robust segmentation of anatomical structures from magnetic resonance images is valuable in many computer-aided clinical tasks. Traditional codec networks are not satisfactory because of their low accuracy of edge segmentation, the low recognition rate of the target, and loss of detailed information. To address these problems, this study proposes a series of improved models for semantic segmentation and progressively optimizes them from the three aspects of convolution module, codec unit, and feature fusion. Instead of the standard convolution structure, we apply a new type of convolution module for the feature extraction. The networks integrate a multi-path method to obtain richer-detail edge information. Finally, a dense network is utilized to strengthen the ability of the feature fusion and integrate more different-level information. The evaluation of the Accuracy, Dice coefficient, and Jaccard index led to values of 0.9855, 0.9185, and 0.8507, respectively. These metrics of the best network increased by 1.0%, 4.0%, and 6.1%, respectively. Boundary F1-Score reached 0.9124 indicating that the proposed networks can segment smaller targets to obtain smoother edges. Our methods obtain more key information than traditional methods and achieve superiority in segmentation performance.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Humans
  • Magnetic Resonance Imaging*
  • Models, Theoretical*
  • Neural Networks, Computer*
  • Spine / diagnostic imaging*
  • Tomography, X-Ray Computed*

Grants and funding

The study was supported by the National Natural Science Foundation of China under Grant No. 33518001, Grant No.61372193, and Grant No.61901304, and Guangdong Natural Science Foundation under Grant No.07010869. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. There was no additional external funding received for this study.