The study aimed to identify the effects of situational (match location, match outcome and strength of team/opponent team) and environmental (ambient temperature, relative humidity, WBGT, ground and weather condition) factors on the physical and technical activity of elite football on individual playing positions. Physical and technical activity were collected from 779 football players competing in the German Bundesliga during 5 domestic seasons, from 2014/2015 to 2018/2019, totalling 1530 matches. The data on players' physical and technical activity was taken from the IMPIRE AG system. Based on the available data, 11 variables were selected to quantify the match activity profiles of players. The results showed that situational variables had major effects on the technical performance (especially number of passes performed) but minor effects on physical performance. In turn, among the analysed environmental factors, temperature is the most sensitive, which affects the Total Distance and Sprint Efforts of players in all five positions. This investigation demonstrated that, given that passing is a key technical activity in modern football, players and training staff should be particularly aware that passing maybe affected by situational variables. Professional players are able to react and adapt to various environmental conditions, modifying physical activity depending on the needs in German Bundesliga. These results could help coaches and analysts to better understand the influences of situational and environmental variables on individual playing positions during the evaluation of players' physical and technical performance.