Integrative and Conjugative Element-Mediated Azithromycin Resistance in Multidrug-Resistant Salmonella enterica serovar Albany

Yu-Ping Hong; Ying-Tsong Chen; You-Wun Wang; Bo-Han Chen; Ru-Hsiou Teng; Yi-Syong Chen; Chien-Shun Chiou

doi:10.1128/AAC.02634-20

Integrative and Conjugative Element-Mediated Azithromycin Resistance in Multidrug-Resistant Salmonella enterica serovar Albany

Antimicrob Agents Chemother. 2023 May 1;65(5):e02634-20. doi: 10.1128/AAC.02634-20. Epub 2021 Mar 8.

Authors

Yu-Ping Hong^{1

2}, Ying-Tsong Chen², You-Wun Wang¹, Bo-Han Chen¹, Ru-Hsiou Teng¹, Yi-Syong Chen¹, Chien-Shun Chiou³

Affiliations

¹ Centers for Disease Control, Taichung, Taiwan.
² National Chung Hsing University, Taichung, Taiwan.
³ Centers for Disease Control, Taichung, Taiwan nipmcsc@cdc.gov.tw.

Abstract

We identified an erm42-carrying integrative and conjugative element, ICE_erm42, in 26.4% of multidrug-resistant Salmonella enterica serovar Albany isolates recovered from human salmonellosis between 2014 and 2019 in Taiwan. ICE_erm42-carrying strains displayed high-level resistance to azithromycin and the element could move into the phylogenetically distant Vibrio cholerae via conjugation.