A Comprehensive Review of COVID-19 Associated Neurological Manifestations

S D Med. 2020 Dec;73(12):569-571.

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing COVID-19 utilizes the angiotensin-converting enzyme 2 (ACE-2) receptor of cells in order to gain entry and continue infection. Recent literature has focused on acute respiratory distress syndrome (ARDS) and other associated pulmonary complications; however, only a scarce amount of literature exists on neurological complications. Such complications also pose a high morbidity in these patients. The exact pathogenesis of nervous system involvement by COVID-19 still remains poorly understood. The aim of this article is to review the neurological symptoms seen in COVID-19 infection and discuss the probable pathogenesis, management and outcome of associated neurological complications.

Publication types

  • Review

MeSH terms

  • COVID-19* / complications
  • Humans
  • Nervous System Diseases* / etiology
  • SARS-CoV-2