Chemistry and biology of spiroacetals from myxobacteria

Michael Ricca; Mark A Rizzacasa

doi:10.1039/d1ob00026h

Chemistry and biology of spiroacetals from myxobacteria

Org Biomol Chem. 2021 Apr 7;19(13):2871-2890. doi: 10.1039/d1ob00026h. Epub 2021 Mar 8.

Authors

Michael Ricca¹, Mark A Rizzacasa

Affiliation

¹ School of Chemistry, The Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Victoria 3010, Australia. masr@unimelb.edu.au.

PMID: 33683270
DOI: 10.1039/d1ob00026h

Abstract

This review details the isolation, biosynthesis, biological activity and synthesis of spiroacetals from the myxobacterium Sorangium cellulosum. The strategies utilised to access the challenging structures and stereochemistry of these natural products are highlighted.

Publication types

Review

MeSH terms

Acetals / chemistry
Acetals / metabolism*
Biological Products / chemistry
Biological Products / metabolism*
Molecular Conformation
Sorangium / chemistry
Sorangium / metabolism
Spiro Compounds / chemistry
Spiro Compounds / metabolism*
Stereoisomerism

Substances

Acetals
Biological Products
Spiro Compounds

Supplementary concepts

Sorangium cellulosum