Application of wastewater-based epidemiology to investigate stimulant drug, alcohol and tobacco use in Lithuanian communities

Sci Total Environ. 2021 Jul 10:777:145914. doi: 10.1016/j.scitotenv.2021.145914. Epub 2021 Feb 19.

Abstract

WBE was applied to evaluate illicit drug (i.e. amphetamine, cocaine, MDMA and methamphetamine), alcohol and tobacco use in three Lithuanian cities in 2018 and 2019. Considerable concentrations of methamphetamine and MDMA were found in the three locations, suggesting a specific Lithuanian consumption pattern. Yet, unexpected high concentrations of amphetamine (>4 μg/L) were detected in two samples of Kaunas in 2018. Through the use of chiral analysis and non-target and suspect drug precursor compound screening, these extreme values were confirmed to be the result of direct disposal of amphetamine in the sewers. Furthermore, substantial alcohol use was measured in the three investigated catchment populations of Lithuania with almost 4 standard drinks/day/inhabitant aged 15+ on average in 2019. For tobacco, an average of 5.6 cigarettes/day/inhabitant aged 15+ in 2019 was reported with large discrepancies between WBE figures and sales data, potentially highlighting illegal trade of tobacco products.

Keywords: Dumping events; Geotemporal resolution; Lithuania; Substance use; Wastewater-based epidemiology.

MeSH terms

  • Adolescent
  • Cities
  • Humans
  • Lithuania / epidemiology
  • Substance Abuse Detection
  • Substance-Related Disorders*
  • Tobacco Use
  • Wastewater / analysis
  • Wastewater-Based Epidemiological Monitoring
  • Water Pollutants, Chemical* / analysis

Substances

  • Waste Water
  • Water Pollutants, Chemical