NiFe2O4 nanospheres functionalized with 2-(2, 4-Dihydroxyphenyl)-3, 5, 7-trihydroxychromen-4-one for selective solid-phase microextraction of aluminium

Bandar A Alyami; Ashraf M Mahmoud; Saad A Alkahtani; Mohamed M El-Wekil

doi:10.1016/j.talanta.2021.122167

NiFe₂O₄ nanospheres functionalized with 2-(2, 4-Dihydroxyphenyl)-3, 5, 7-trihydroxychromen-4-one for selective solid-phase microextraction of aluminium

Talanta. 2021 May 1:226:122167. doi: 10.1016/j.talanta.2021.122167. Epub 2021 Jan 30.

Authors

Bandar A Alyami¹, Ashraf M Mahmoud², Saad A Alkahtani³, Mohamed M El-Wekil⁴

Affiliations

¹ Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Najran University, Najran, Saudi Arabia.
² Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Najran University, Najran, Saudi Arabia; Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt.
³ Department of Clinical Pharmacy, College of Pharmacy, Najran University, Najran, Saudi Arabia.
⁴ Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt. Electronic address: mohamed.elwakeel@pharm.aun.edu.eg.

PMID: 33676709
DOI: 10.1016/j.talanta.2021.122167

Abstract

Herein, a rational combination of dispersive solid-phase sorbent and 2-(2, 4-Dihydroxyphenyl)-3, 5, 7-trihydroxychromen-4-one (morin) was proposed for sensitive and selective determination of Al³⁺ ion. Nickel ferrite nanospheres (NiFe₂O₄ NS) functionalized with morin was used to preconcentrate and estimate Al³⁺ via the formation of fluorescent complex at pH 7.0. The functionalization was assisted by anionic surfactant sodium dodecyl sulphate (SDS) and ultrasonication. The results revealed that the fluorescence intensity of Al-morin/SDS@ NiFe₂O₄ NS is higher than Al-morin. Functionalization of NiFe₂O₄ NS with morin was confirmed by scanning electron microscopy (SEM), transmission electron microscopy (TEM), energy-dispersive X-ray spectroscopy (EDX), Fourier transform infrared spectroscopy (FTIR), powder X-ray diffractometer (PXRD), and fluorescence spectroscopy. Under the optimum conditions, the fluorescence intensity increased with increasing of Al³⁺ concentrations in the range of 0.28-500.0 ng mL^-1 with LOD (S/N = 3) of 0.09 ng mL^-1. The method was applied for the determination of Al³⁺ in natural waters and human serum samples with recoveries % of 97-104% and RSDs % of 2-4%.

Keywords: Aluminum ion; Morin; Natural waters and blood serum samples; Nickel ferrite nanospheres; Sodium dodecyl sulphate.