Analysis of Recent Bio-/Nanotechnologies for Coronavirus Diagnosis and Therapy

Sensors (Basel). 2021 Feb 20;21(4):1485. doi: 10.3390/s21041485.

Abstract

Despite barrier measures and physical distancing tailored by the populations worldwide, coronavirus continues to spread causing severe health and social-economic problems. Therefore, researchers are focusing on developing efficient detection and therapeutic platforms for SARS-CoV2. In this context, various biotechnologies, based on novel molecules targeting the virus with high specificity and affinity, have been described. In parallel, new approaches exploring nanotechnology have been proposed for enhancing treatments and diagnosis. We discuss in the first part of this review paper, the different biosensing and rapid tests based on antibodies, nucleic acids and peptide probes described since the beginning of the pandemic. Furthermore, given their numerous advantages, the contribution of nanotechnologies is also highlighted.

Keywords: biomolecules; biosensing; coronavirus; diagnosis; drug delivery; nanoparticles; treatment.

Publication types

  • Review

MeSH terms

  • Biosensing Techniques
  • Biotechnology / trends*
  • COVID-19 / diagnosis*
  • COVID-19 / therapy*
  • Humans
  • Nanotechnology / trends*