Incidence, predictors, and outcomes of post-thrombectomy seizures in the extended time window

Epilepsy Behav Rep. 2021 Jan 7:15:100426. doi: 10.1016/j.ebr.2020.100426. eCollection 2021.

Abstract

Mechanical thrombectomy 6-24 h after the last time where a patient was known to be without signs or symptoms of a stroke is the standard of care for patients with a stroke due to large vessel occlusion. This is referred to as thrombectomy within an extended time window. There have been very few studies looking at patients who had seizures within the first week (early post-stroke seizures) following mechanical thrombectomy in this extended time window. Our study suggests that this group of patients does not have a higher incidence of early post stroke seizures. Our findings do reveal however, that patients who do have early post-stroke seizures may have a less favorable functional outcome at 90 days than those who did not develop early seizures. Hence, rapid identification and subsequent treatment of seizures in these patients is important.

Keywords: Acute ischemic stroke; Extended window thrombectomy; Large vessel occlusion; Seizure.