Preliminary evaluation of the larvicidal activity of extracts and fractions from Ocotea nutans (Nees) Mez against Aedes aegypti

Rev Soc Bras Med Trop. 2021 Feb 26:54:e05762020. doi: 10.1590/0037-8682-0576-2020. eCollection 2021.

Abstract

Introduction: Aedes aegypti is the main vector of dengue and yellow fever. Recently, the use of plant-sourced larvicides has gained momentum.

Methods: The hydroethanolic extracts and fractions ofOcotea nutansleaves and stems were bioassayed to determine the larvicidal efficacy of these samples.

Results: S-HEX (hexane fraction from the crude stem extract) demonstrated high potential for controlling third-stage larvae, with an LC50 of 14.14 µg.mL-1 (concentration required to inhibit 50% of the treated larvae).

Conclusions: Extracts from O. nutans were effective against third-stage larvae ofA. aegyptiafter 24 h of exposure.

MeSH terms

  • Aedes*
  • Animals
  • Insecticides* / pharmacology
  • Larva
  • Mosquito Vectors
  • Ocotea*
  • Plant Extracts / pharmacology
  • Plant Leaves

Substances

  • Insecticides
  • Plant Extracts