The find of COVID-19 vaccine: Challenges and opportunities

J Infect Public Health. 2021 Mar;14(3):389-416. doi: 10.1016/j.jiph.2020.12.025. Epub 2020 Dec 30.

Abstract

Severe acute respiratory syndrome coronavirus (SARS-CoV-2), a novel corona virus, causing COVID-19 with Flu-like symptoms is the first alarming pandemic of the third millennium. SARS-CoV-2 belongs to beta coronavirus as Middle East respiratory syndrome coronavirus (MERS-CoV). Pandemic COVID-19 owes devastating mortality and destructively exceptional consequences on Socio-Economics life around the world. Therefore, the current review is redirected to the scientific community to owe comprehensive visualization about SARS-CoV-2 to tackle the current pandemic. As systematically shown through the current review, it indexes unmet medical problem of COVID-19 in view of public health and vaccination discovery for the infectious SARS-CoV-2; it is currently under-investigational therapeutic protocols, and next possible vaccines. Furthermore, the review extensively reports the precautionary measures to achieve" COVID-19/Flatten the curve". It is concluded that vaccines formulation within exceptional no time in this pandemic is highly recommended, via following the same protocols of previous pandemics; MERS-CoV and SARS-CoV, and excluding some initial steps of vaccination development process.

Keywords: COVID-19; Flatten the curve; Infectious diseases; SARS-CoV-2; Vaccination; Viral pandemic.

Publication types

  • Review

MeSH terms

  • COVID-19 / prevention & control*
  • COVID-19 Vaccines / therapeutic use*
  • Humans
  • Pandemics / prevention & control

Substances

  • COVID-19 Vaccines