Machine learning and augmented human intelligence use in histomorphology for haematolymphoid disorders

Pathology. 2021 Apr;53(3):400-407. doi: 10.1016/j.pathol.2020.12.004. Epub 2021 Feb 25.

Abstract

Advances in digital pathology have allowed a number of opportunities such as decision support using artificial intelligence (AI). The application of AI to digital pathology data shows promise as an aid for pathologists in the diagnosis of haematological disorders. AI-based applications have embraced benign haematology, diagnosing leukaemia and lymphoma, as well as ancillary testing modalities including flow cytometry. In this review, we highlight the progress made to date in machine learning applications in haematopathology, summarise important studies in this field, and highlight key limitations. We further present our outlook on the future direction and trends for AI to support diagnostic decisions in haematopathology.

Keywords: Machine learning; artificial intelligence; haematopathology; leukaemia; lymphoma.

Publication types

  • Review

MeSH terms

  • Artificial Intelligence
  • Flow Cytometry
  • Hematology*
  • Humans
  • Leukemia / diagnosis*
  • Leukemia / pathology
  • Lymphoma / diagnosis*
  • Lymphoma / pathology
  • Machine Learning*