Antibacterial efficacy of facile cyanobacterial silver nanoparticles inferred by antioxidant mechanism

Mater Sci Eng C Mater Biol Appl. 2021 Mar:122:111888. doi: 10.1016/j.msec.2021.111888. Epub 2021 Jan 15.

Abstract

Nanoparticles (NPs) have gained importance in technological advances owing to their user friendly enhanced and efficient physical, chemical, and biological characteristics compared to their bulk counterparts. Biological synthesis of NPs by using a microorganism, enzymes, or plant extracts offers a greener and eco-friendly approach besides many advantages over physical or chemical approaches. This study reports the biosynthesis of silver nanoparticles (AgNPs) using Nostoc muscorum NCCU 442 aqueous extract as the reducing and capping agent for AgNPs synthesis. The synthesized nanoparticles were characterized by UV-VIS spectrum, SEM, EDS, TEM, AFM, DLS and XRD. Results showed distinguishing polycrystalline nature of synthesized AgNPs with surface plasmon significant band in the size range of 6-45nm with average 30 size nm. FT-IR study revealed the role of secondary metabolites present in aqueous extract for the synthesis of AgNPs. Biological activities of purified AgNPs as antioxidant and antibacterial potential showed the highest antibacterial activity against Staphylococcus aureus MTCC 902.

Keywords: Antibacterial activity; Antioxidant activity; Cyanobacteria; Green synthesis; Silver nanoparticles.

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Antioxidants / pharmacology
  • Metal Nanoparticles*
  • Plant Extracts / pharmacology
  • Silver*
  • Spectroscopy, Fourier Transform Infrared

Substances

  • Anti-Bacterial Agents
  • Antioxidants
  • Plant Extracts
  • Silver