Medullary and Hypothalamic Functional Magnetic Imaging During Acute Hypoxia in Tracing Human Peripheral Chemoreflex Responses

Hypertension. 2021 Apr;77(4):1372-1382. doi: 10.1161/HYPERTENSIONAHA.120.16385. Epub 2021 Mar 1.

Authors

Darius A Gerlach¹, Jorge Manuel^{1

2}, Alex Hoff¹, Hendrik Kronsbein^{1

3}, Fabian Hoffmann¹, Karsten Heusser¹, Heimo Ehmke³, Jens Jordan^{1

4}, Jens Tank^#¹, Florian Beissner^#²

Affiliations

¹ Institute of Aerospace Medicine, German Aerospace Center (DLR), Cologne, Germany (D.A.G., J.M., A.H., H.K., F.H., K.H., J.J., J.T.).
² Institute for Neuroradiology, Hannover Medical School, Germany (J.M., F.B.).
³ Institute of Cellular and Integrative Physiology, University Medical Center Eppendorf, Hamburg, Germany (H.K., H.E.).
⁴ Chair of Aerospace Medicine, University of Cologne, Germany (J.J.).

^# Contributed equally.

PMID: 33641354
DOI: 10.1161/HYPERTENSIONAHA.120.16385

Abstract

[Figure: see text].

Keywords: blood pressure; brain stem; hypothalamus; hypoxia; magnetic resonance imaging.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adult
Carotid Body* / metabolism
Carotid Body* / physiopathology
Healthy Volunteers
Humans
Hypothalamus* / diagnostic imaging
Hypothalamus* / physiopathology
Hypoxia / physiopathology*
Magnetic Resonance Imaging / methods*
Male
Medulla Oblongata* / diagnostic imaging
Medulla Oblongata* / physiopathology
Monitoring, Physiologic / methods
Research Design

Associated data

DRKS/DRKS00013101