Nasal angiofibroma treatment outcome using intensity-modulated radiation therapy in a dog

Vet Radiol Ultrasound. 2021 Jul;62(4):e40-e43. doi: 10.1111/vru.12961. Epub 2021 Feb 26.

Abstract

A 6-year-old dog presented with a modified Adams stage 3 angiofibroma of the right nasal cavity, causing fluid accumulation along the right frontal sinus. Treatment consisted of step-and-shoot intensity-modulated radiation therapy in 12 daily treatments of 3.5 Gy, for a total dose of 42 Gy to 95% of the planning target volume. The dog developed self-limiting grade 2 oral mucositis which resolved within 2 weeks of course completion. A recheck exam 668 days after treatment confirmed a stable disease response by RECIST and a tumor volume decrease of 55.4%.

MeSH terms

  • Angiofibroma / pathology
  • Angiofibroma / radiotherapy
  • Angiofibroma / veterinary*
  • Animals
  • Dog Diseases / pathology
  • Dog Diseases / radiotherapy*
  • Dogs
  • Humans
  • Male
  • Nose Neoplasms / pathology
  • Nose Neoplasms / radiotherapy
  • Nose Neoplasms / veterinary*
  • Radiotherapy Dosage / veterinary
  • Radiotherapy Planning, Computer-Assisted / veterinary
  • Radiotherapy, Intensity-Modulated / veterinary*
  • Treatment Outcome
  • Tumor Burden