Neurologic complications of congenital heart disease in adults

Handb Clin Neurol. 2021:177:15-22. doi: 10.1016/B978-0-12-819814-8.00011-1.

Abstract

Congenital heart disease (CHD) is a heterogeneous group of structural abnormalities of the cardiovascular system that are present at birth. Advances in childhood medical and surgical treatment have led to increasing numbers of adults with CHD. Neurological complications of CHD in adults are varied and can include an increased risk of stroke not only related to the underlying congenital defect and its surgical management but also due to atherosclerotic disease associated with advancing age. In addition to cerebrovascular events, CHD in adults is also associated with an increased risk of neurodevelopmental disorders, cognitive impairment, psychiatric disease, and epilepsy. Collaborative multidisciplinary care with contributions from neurologists and cardiologists with expertise in adult CHD is necessary to provide optimal long-term care for this complex and rapidly evolving population.

Keywords: Autism; Brain hemorrhage; Cognition; Congenital heart disease; Epilepsy; Ischemic stroke.

MeSH terms

  • Adult
  • Heart Defects, Congenital* / complications
  • Heart Defects, Congenital* / therapy
  • Humans
  • Neurodevelopmental Disorders*
  • Stroke*