Efficacy and safety of EUS-guided hepaticoesophagostomy (EUS-HES) for malignant biliary obstruction: the first case series

Surg Endosc. 2022 Feb;36(2):1117-1122. doi: 10.1007/s00464-021-08378-1. Epub 2021 Feb 24.

Abstract

Background: EUS-guided hepaticoesophagostomy (EUS-HES) was reported as an alternative procedure when puncture through the esophagus was inevitable. However, the existing data is very limited. We aimed to evaluate the efficacy and safety of EUS-HES in patients with difficult malignant biliary obstruction.

Methods: All cases who underwent EUS-HES at our institute were retrospectively reviewed.

Results: A total of 11 patients underwent EUS-HES from January 2011 to December 2017. Five were male, and the mean age was 57.9 ± 6.3 years. The majority of the patients (8 out of 11 patients) had a biliary obstruction caused by cholangiocarcinoma. The technical success was 100%. The mean procedure time was 73.2 ± 37.6 min. The main reason for EUS-HES was the improper alignment of the bile duct due to left lobe hypertrophy. The clinical success was 90.9%. The mean overall survival was 97.8 ± 68.5 days. No major procedure-related complication, particularly pneumomediastinum, occurred.

Conclusions: EUS-HES is a technically feasible and safe procedure to provide biliary drainage, especially in patients with left hepatic lobe hypertrophy. Using a bougie dilator instead of balloon dilation can avoid previously reported complications.

Keywords: EUS-guided biliary drainage; EUS-guided hepaticoesophagostomy; Failed ERCP; Malignant biliary obstruction.

MeSH terms

  • Cholangiopancreatography, Endoscopic Retrograde / adverse effects
  • Cholestasis* / etiology
  • Drainage / methods
  • Endosonography* / methods
  • Female
  • Humans
  • Male
  • Middle Aged
  • Retrospective Studies
  • Stents