Two new terpenes from the aerial parts of Clematis chinensis Osbeck

Nat Prod Res. 2022 Aug;36(15):3825-3832. doi: 10.1080/14786419.2021.1889541. Epub 2021 Feb 22.

Abstract

Two new acyclic sesquiterpenoids (1-2) and fourteen known monocyclic monoterpenoids (3-16) were isolated from the aerial parts of Clematis chinensis Osbeck. All compounds were isolated from C. chinensis for the first time. The structures of all compounds were characterized by spectroscopic methods (1 D, 2 D NMR and HRESIMS). In-vitro cytotoxic activity against two human cancer cell lines (MGC-803 and Ishikawa) of all the compounds were evaluated by CCK-8 assay.

Keywords: Clematis chinensis Osbeck; Terpenes; aerial parts; cytotoxicity.

MeSH terms

  • Clematis* / chemistry
  • Drugs, Chinese Herbal* / chemistry
  • Humans
  • Magnetic Resonance Spectroscopy
  • Molecular Structure
  • Plant Components, Aerial / chemistry
  • Terpenes / analysis
  • Terpenes / pharmacology

Substances

  • Drugs, Chinese Herbal
  • Terpenes