Extensive cerebellar involvement and cognitive impairment in COVID-19-associated acute necrotizing encephalopathy

Dumitru Ciolac; Igor Crivorucica; Eremei Zota; Nadejda Gorincioi; Daniela Efremova; Diana Manea; Veaceslav Crivorucica; Mihail Ciocanu; Stanislav A Groppa

doi:10.1177/1756286420985175

Extensive cerebellar involvement and cognitive impairment in COVID-19-associated acute necrotizing encephalopathy

Ther Adv Neurol Disord. 2021 Feb 3:14:1756286420985175. doi: 10.1177/1756286420985175. eCollection 2021.

Authors

Dumitru Ciolac¹, Igor Crivorucica¹, Eremei Zota¹, Nadejda Gorincioi¹, Daniela Efremova¹, Diana Manea¹, Veaceslav Crivorucica¹, Mihail Ciocanu¹, Stanislav A Groppa²

Affiliations

¹ Institute of Emergency Medicine, Chisinau, Republic of Moldova.
² Department of Neurology, Institute of Emergency Medicine, Toma Ciorba Street 1, Chisinau, 2004, Republic of Moldova.

Abstract

Neurological complications of the newly appeared severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are increasingly recognized. Here, we report a case of a young male presenting with a clinical and neuroimaging scenario of an acute necrotizing encephalopathy related to the coronavirus disease 2019 (COVID-19). This case is notable by its distinct pattern of magnetic resonance imaging findings of an extensive involvement of the cerebellum, and emergence of cognitive and behavioral impairment.

Keywords: COVID-19; SARS-CoV-2; acute necrotizing encephalopathy; cerebellum.

Publication types

Case Reports