Hexavalent chromium: Regulation and health effects

J Trace Elem Med Biol. 2021 May:65:126729. doi: 10.1016/j.jtemb.2021.126729. Epub 2021 Feb 12.

Abstract

Despite the knowledge about heavy metals toxicity on humans, its use is widely spread mainly for industrial processes. Chromium is an element that belongs to this group and although it is present in our daily diet, it can also be harmful for humans, causing skin allergies and increasing the risk of lung cancer, among other health effects reported. In this review, we highlight its nutritional role, its toxicokinetic and toxicodynamic in humans, its regulation in the industry and the biomonitoring proposal of this element in blood and urine samples with the aim to control the level of exposure of the workers in military industry and also of the general population.

Keywords: Chromium; Health effects; Occupational asthma; Regulation; Toxicity.

Publication types

  • Review

MeSH terms

  • Chromium / adverse effects
  • Chromium / analysis
  • Chromium / metabolism*
  • Dermatitis / blood
  • Dermatitis / metabolism*
  • Dermatitis / urine
  • Environmental Monitoring
  • Humans
  • Lung Neoplasms / blood
  • Lung Neoplasms / metabolism*
  • Lung Neoplasms / urine

Substances

  • Chromium
  • chromium hexavalent ion