Recent advances in design of lanthanide-containing NIR-II luminescent nanoprobes

Yingjie Yang; Datao Tu; Yunqin Zhang; Peng Zhang; Xueyuan Chen

doi:10.1016/j.isci.2021.102062

Recent advances in design of lanthanide-containing NIR-II luminescent nanoprobes

iScience. 2021 Jan 20;24(2):102062. doi: 10.1016/j.isci.2021.102062. eCollection 2021 Feb 19.

Authors

Yingjie Yang^{1

2}, Datao Tu^{1

3}, Yunqin Zhang^{1

2}, Peng Zhang¹, Xueyuan Chen^{1

2

3}

Affiliations

¹ CAS Key Laboratory of Design and Assembly of Functional Nanostructures, and Fujian Key Laboratory of Nanomaterials, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou 350002, China.
² University of Chinese Academy of Sciences, Beijing 100049, China.
³ Fujian Science & Technology Innovation Laboratory for Optoelectronic Information of China, Fuzhou, Fujian 350108, China.

Abstract

Luminescent biosensing in the second near-infrared window (NIR-II, 1000-1700 nm) region, which has weak tissue scattering and low autofluorescence, draws extensive attention owing to its deep tissue penetration, good spatial resolution and high signal-to-background ratio. As a new generation of NIR-II probes, lanthanide (Ln³⁺)-containing nanoprobes exhibit several superior properties. With the rapid development of Ln³⁺-containing NIR-II nanoprobes, many significant advances have been accomplished in their optical properties tuning and surface functional modification for further bioapplications. Rather than being exhaustive, this review aims to survey the recent advances in the design strategies of inorganic Ln³⁺-containing NIR-II luminescent nanoprobes by highlighting their optical performance optimization and surface modification approaches. Moreover, challenges and opportunities for this kind of novel NIR-II nanoprobes are envisioned.

Keywords: molecular inorganic chemistry; nanomaterials; optical materials.

Publication types

Review