Flat epithelial atypia: What the radiologist needs to know in 2021

Clin Imaging. 2021 Jul:75:150-156. doi: 10.1016/j.clinimag.2021.01.035. Epub 2021 Feb 2.

Abstract

The World Health Organization defines flat epithelial atypia (FEA), as a "presumably neoplastic intraductal alteration characterized by the replacement of native epithelial cells by a single layer or three to five layers of mildly atypical cells.". In this article, we will review FEA and compare its characteristics and differences with other atypical high-risk breast lesions. In addition, the imaging appearance of FEA will be described. Finally, we will discuss current outcomes and provide an update on its management based on the last recommendations.

Keywords: Breast imaging; High-risk lesion.

Publication types

  • Review

MeSH terms

  • Breast
  • Breast Neoplasms* / diagnostic imaging
  • Carcinoma, Intraductal, Noninfiltrating*
  • Epithelial Cells
  • Humans
  • Precancerous Conditions*
  • Radiologists