Insights into the role of placenta thickness as a predictive marker of perinatal outcome

J Int Med Res. 2021 Feb;49(2):300060521990969. doi: 10.1177/0300060521990969.

Abstract

The placenta is a transitory organ indispensable for normal fetal maturation and growth. Recognition of abnormal placental variants is important in clinical practice, and a broader understanding of the significance of placental variants would help clinicians better manage affected pregnancies. Increased thickness of the placenta is reported to be a nonspecific finding but it is associated with many maternal and fetal abnormalities, including preeclampsia and abnormal fetal growth. In this review, we address the questions regarding the characteristics of placenta thickness and the relationship between thickened placenta and poor pregnancy outcomes.

Keywords: Placenta thickness; fetal complications; gestational diabetes; maternal complications; placentomegaly; preeclampsia.

Publication types

  • Review

MeSH terms

  • Biomarkers
  • Female
  • Fetus
  • Humans
  • Placenta*
  • Pre-Eclampsia* / diagnosis
  • Pregnancy
  • Pregnancy Outcome

Substances

  • Biomarkers